FMP is a Platinum(IV) complexe. FMP significantly upregulates the expression of gamma-H2AX and p53. FMP increases the production of ROS. FMP markedly upregulates the expressions of Apoptosis-related proteins (DR5, Fas, caspase-8, Cyt-c, caspase-3, cleaved-PARP1, Bax). FMP shows antiproliferative activity against breast cancer[1].
Molekulargewicht:
640.33
Formel:
C18H18Cl2N2O7Pt
Target-Kategorie:
Apoptosis,Bcl-2 Family,Caspase,MDM-2/p53,PARP,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
