FMP is a Platinum(IV) complexe. FMP significantly upregulates the expression of gamma-H2AX and p53. FMP increases the production of ROS. FMP markedly upregulates the expressions of Apoptosis-related proteins (DR5, Fas, caspase-8, Cyt-c, caspase-3, cleaved-PARP1, Bax). FMP shows antiproliferative activity against breast cancer[1].
Molecular Weight:
640.33
Formula:
C18H18Cl2N2O7Pt
Target:
Apoptosis,Bcl-2 Family,Caspase,MDM-2/p53,PARP,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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