XJTU-L453 is a PI3Kalpha inhibitor with an IC50 value of 0.4 nM. XJTU-L453 can inhibit the proliferation of breast cancer cell lines T47D and MCF7, with IC50 values of 0.2 µM and 0.5 µM, respectively. XJTU-L453 can inhibit the PI3K pathway, induce cell cycle arrest, and trigger cell apoptosis (apoptosis). XJTU-L453 also has antitumor activity in MCF7 xenograft mice[1].
Molekulargewicht:
390.44
CAS Nummer:
[3008290-92-1]
Formel:
C22H22N4O3
Target-Kategorie:
Apoptosis,PI3K
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
