PROTAC 20S proteasome subunit beta5 degrader 1 Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC 20S proteasome subunit beta5 degrader 1 Preis auf Anfrage
• Artikelnummer: MCE-HY-169134
• Hersteller Artikelnummer: HY-169134
• Alternativnummer: MCE-HY-169134-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC 20S proteasome subunit beta5 degrader 1 (compound 12f) is a targeted degrader of PROTAC for 20S proteasome subunit beta5, with a DC50 value of 0.11 µM in FaDu cells. PROTAC 20S proteasome subunit beta5 degrader 1 disrupts the cell cycle, promotes apoptosis, and inhibits cell proliferation and migration in both FaDu and KM3/BTZ cells. PROTAC 20S proteasome subunit beta5 degrader 1 can be used to study the resistance of pharyngeal cancer and multiple myeloma to Bortezomib (HY-10227) (Pink: Target protein ligand (HY-10227), Blue: E3 ligase ligand (HY-103596), Black: Linker (HY-169142))[1].

Produkteigenschaften

• Molekulargewicht: 986.95
• Formel: C54H67BN6O11
• Target-Kategorie: Apoptosis,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound