PROTAC 20S proteasome subunit beta5 degrader 1 Preis auf Anfrage

Product Overview

• Article Name: PROTAC 20S proteasome subunit beta5 degrader 1 Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-169134
• Supplier Catalog Number: HY-169134
• Alternative Catalog Number: MCE-HY-169134-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC 20S proteasome subunit beta5 degrader 1 (compound 12f) is a targeted degrader of PROTAC for 20S proteasome subunit beta5, with a DC50 value of 0.11 µM in FaDu cells. PROTAC 20S proteasome subunit beta5 degrader 1 disrupts the cell cycle, promotes apoptosis, and inhibits cell proliferation and migration in both FaDu and KM3/BTZ cells. PROTAC 20S proteasome subunit beta5 degrader 1 can be used to study the resistance of pharyngeal cancer and multiple myeloma to Bortezomib (HY-10227) (Pink: Target protein ligand (HY-10227), Blue: E3 ligase ligand (HY-103596), Black: Linker (HY-169142))[1].

Product Properties

• Molecular Weight: 986.95
• Formula: C54H67BN6O11
• Target: Apoptosis,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound