JNK-1-IN-4, CAS [[3047795-60-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: JNK-1-IN-4, CAS [[3047795-60-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-169177
• Hersteller Artikelnummer: HY-169177
• Alternativnummer: MCE-HY-169177-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

JNK-1-IN-4 (Compound E1) is an inhibitor for JNK, that inhibits JNK-1, JNK-2 and JNK-3 with IC50s of 2.7, 19.0 and 9.0 nM, respectively. JNK-1-IN-4 inhibits the phosphorylation of c-Jun, and reduces the expression of TGF-beta1-induced EMT marker proteins, such as fibronectin and alpha-SMA. JNK-1-IN-4 exhibits good pharmacokinetic characteristics with a bioavailability of 69%. JNK-1-IN-4 exhibits anti-fibrotic effect in Bleomycin (HY-17565)-induced mice idiopathic pulmonary fibrosis models[1].

Produkteigenschaften

• Molekulargewicht: 501.38
• CAS Nummer: [3047795-60-5]
• Formel: C22H25BrN6O3
• Target-Kategorie: JNK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound