NLRP3-IN-55 (Compound 19) is a potent NLRP3 inhibitor (IC50 = 0.34 µM). NLRP3-IN-55 directly targets the NLRP3 protein (KD = 0.45 µM), blocking the assembly and activation of the NLRP3 inflammasome, leading to anti-inflammatory effects and inhibition of cellular pyroptosis[1].
Molekulargewicht:
561.04
Formel:
C32H30ClFN2O4
Target-Kategorie:
NOD-like Receptor (NLR),Pyroptosis
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
