NLRP3-IN-55 (Compound 19) is a potent NLRP3 inhibitor (IC50 = 0.34 µM). NLRP3-IN-55 directly targets the NLRP3 protein (KD = 0.45 µM), blocking the assembly and activation of the NLRP3 inflammasome, leading to anti-inflammatory effects and inhibition of cellular pyroptosis[1].
Molecular Weight:
561.04
Formula:
C32H30ClFN2O4
Target:
NOD-like Receptor (NLR),Pyroptosis
Application Notes:
MCE Product type: Reference compound1
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