Abeta-IN-10 (Compound Alz -5) is a bifunctional copper chelator and an inhibitor for beta-amyloid (Abeta), that interacts with Abeta aggregates and reduces the neurotoxicity. Abeta-IN-10 exhibits antioxidant efficacy, reveals moderate cytotoxicity with the presence of CuCl2 in SH-SY5Y and HepG2 with IC50 of 65.5, 31.2 µM. Abeta-IN-10 reduces the increase of cell stiffness caused by Abeta[1].
Molekulargewicht:
557.78
Formel:
C30H35N7S2
Target-Kategorie:
Amyloid-beta
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
