Abeta-IN-10 (Compound Alz -5) is a bifunctional copper chelator and an inhibitor for beta-amyloid (Abeta), that interacts with Abeta aggregates and reduces the neurotoxicity. Abeta-IN-10 exhibits antioxidant efficacy, reveals moderate cytotoxicity with the presence of CuCl2 in SH-SY5Y and HepG2 with IC50 of 65.5, 31.2 µM. Abeta-IN-10 reduces the increase of cell stiffness caused by Abeta[1].
Molecular Weight:
557.78
Formula:
C30H35N7S2
Target:
Amyloid-beta
Application Notes:
MCE Product type: Reference compound
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