HPG1860 is an orally active, highly selective and potent FXR agonist, with an EC50 of 18 nM (FXR-luciferase reporter assay). HPG1860 has EC50 values >30.0 µM for TGR5 and 13 other related nuclear receptors (cAMP biological assay). HPG1860 can be used for the research of non-alcoholic steatohepatitis (NASH)[1].
Molekulargewicht:
573.49
Reinheit:
99.9
CAS Nummer:
[2226133-29-3]
Formel:
C27H26Cl2N4O4S
Target-Kategorie:
Aminotransferases (Transaminases) ,FXR
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten