HPG1860 is an orally active, highly selective and potent FXR agonist, with an EC50 of 18 nM (FXR-luciferase reporter assay). HPG1860 has EC50 values >30.0 µM for TGR5 and 13 other related nuclear receptors (cAMP biological assay). HPG1860 can be used for the research of non-alcoholic steatohepatitis (NASH)[1].
Molecular Weight:
573.49
Purity:
99.9
CAS Number:
[2226133-29-3]
Formula:
C27H26Cl2N4O4S
Target:
Aminotransferases (Transaminases) ,FXR
Application Notes:
MCE Product type: Reference compound
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