2-(Cyclohexylmethyl)-plumbagin, CAS [[3033734-59-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: 2-(Cyclohexylmethyl)-plumbagin, CAS [[3033734-59-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-169830
• Hersteller Artikelnummer: HY-169830
• Alternativnummer: MCE-HY-169830-5MG,MCE-HY-169830-1MG,MCE-HY-169830-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

2-(Cyclohexylmethyl)-plumbagin is a derivative of the naphthoquinone compound Plumbagin (HY-N1497). Under nutrient-deprived conditions, 2-(Cyclohexylmethyl)-plumbagin selectively exhibits cytotoxicity against PANC-1 human pancreatic cancer cells (PC50 = 0.11 µM) and reduces the phosphorylation of Akt and mTOR in PANC-1 cells. 2-(Cyclohexylmethyl)-plumbagin also induces apoptosis (Apoptosis) in PANC-1 cells at a concentration of 1 µM. Additionally, 2-(Cyclohexylmethyl)-plumbagin reduces tumor volume and weight in a xenograft MiaPaCa-2 pancreatic cancer mouse model[1].

Produkteigenschaften

• Molekulargewicht: 270.32
• CAS Nummer: [3033734-59-4]
• Formel: C17H18O3
• Target-Kategorie: Apoptosis,Drug Derivative

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound