2-(Cyclohexylmethyl)-plumbagin, CAS [[3033734-59-4]] Preis auf Anfrage

Product Overview

• Article Name: 2-(Cyclohexylmethyl)-plumbagin, CAS [[3033734-59-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-169830
• Supplier Catalog Number: HY-169830
• Alternative Catalog Number: MCE-HY-169830-5MG,MCE-HY-169830-1MG,MCE-HY-169830-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

2-(Cyclohexylmethyl)-plumbagin is a derivative of the naphthoquinone compound Plumbagin (HY-N1497). Under nutrient-deprived conditions, 2-(Cyclohexylmethyl)-plumbagin selectively exhibits cytotoxicity against PANC-1 human pancreatic cancer cells (PC50 = 0.11 µM) and reduces the phosphorylation of Akt and mTOR in PANC-1 cells. 2-(Cyclohexylmethyl)-plumbagin also induces apoptosis (Apoptosis) in PANC-1 cells at a concentration of 1 µM. Additionally, 2-(Cyclohexylmethyl)-plumbagin reduces tumor volume and weight in a xenograft MiaPaCa-2 pancreatic cancer mouse model[1].

Product Properties

• Molecular Weight: 270.32
• CAS Number: [3033734-59-4]
• Formula: C17H18O3
• Target: Apoptosis,Drug Derivative

Application Notes

• Application Notes: MCE Product type: Reference compound