M351-0056 is the agonist for the immune checkpoint protein VISTA, that reduces the secretion of VISTA-induced cytokines, promotes the T-cell proliferation induced by VISTA, and exhibits immunomodulatory activity. M351-0056 ameliorates Imiquimod (HY-B0180)-induced psoriatic dermatitis in mouse models[1].
Molekulargewicht:
447.37
Reinheit:
99.48
CAS Nummer:
[1189495-81-5]
Formel:
C15H12BrFN2O2S3
Target-Kategorie:
VISTA
Anwendungsbeschreibung:
MCE Product type: Reference compound
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