M351-0056 is the agonist for the immune checkpoint protein VISTA, that reduces the secretion of VISTA-induced cytokines, promotes the T-cell proliferation induced by VISTA, and exhibits immunomodulatory activity. M351-0056 ameliorates Imiquimod (HY-B0180)-induced psoriatic dermatitis in mouse models[1].
Molecular Weight:
447.37
Purity:
99.48
CAS Number:
[1189495-81-5]
Formula:
C15H12BrFN2O2S3
Target:
VISTA
Application Notes:
MCE Product type: Reference compound
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