cGAS-IN-4, CAS [[2987886-49-5]]

Produktübersicht

• Artikelname: cGAS-IN-4, CAS [[2987886-49-5]]
• Artikelnummer: MCE-HY-170362
• Hersteller Artikelnummer: HY-170362
• Alternativnummer: MCE-HY-170362-25MG,MCE-HY-170362-50MG,MCE-HY-170362-10MG,MCE-HY-170362-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

cGAS-IN-4 (Compound 36) is an orally active inhibitor for cyclic GMP-AMP synthase (cGAS) with IC50 of 32 nM and 5.8 nM for h-cGAS and m-cGAS. cGAS-IN-4 inhibits the cGAMP in THP-1 cell with an IC50 of 60 nM, which improves the cellular potency. cGAS-IN-4 exhibits anti-inflammatory efficacy in Concanavalin A (HY-P2149)-induced acute liver injury in mouse models[1]. orally active, THP-1, C57Bl/6 mouse, orally active

Produkteigenschaften

• Molekulargewicht: 421.28
• Reinheit: 99.42
• CAS Nummer: [2987886-49-5]
• Formel: C19H18Cl2N4O3
• Target-Kategorie: Cyclic GMP-AMP Synthase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound