SHO1122147 (Compound 7m) affects the mitochondrial electron transport chain, exhibits mitochondrial uncoupling activity (EC50=3.6 µM), and increases the oxygen consumption rate (OCR=69%) and promotes cellular respiration. SHO1122147 is orally active, and can be used in reaearch of obesity and metabolic dysfunction-associated steatohepatitis (MASH)[1].
Molekulargewicht:
338.75
Formel:
C17H11ClN4O2
Target-Kategorie:
Mitochondrial Metabolism
Anwendungsbeschreibung:
MCE Product type: Reference compound
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