SHO1122147 (Compound 7m) affects the mitochondrial electron transport chain, exhibits mitochondrial uncoupling activity (EC50=3.6 µM), and increases the oxygen consumption rate (OCR=69%) and promotes cellular respiration. SHO1122147 is orally active, and can be used in reaearch of obesity and metabolic dysfunction-associated steatohepatitis (MASH)[1].
Molecular Weight:
338.75
Formula:
C17H11ClN4O2
Target:
Mitochondrial Metabolism
Application Notes:
MCE Product type: Reference compound
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