YB-3-17, CAS [[2940242-88-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: YB-3-17, CAS [[2940242-88-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-170405
• Hersteller Artikelnummer: HY-170405
• Alternativnummer: MCE-HY-170405-50MG,MCE-HY-170405-100MG,MCE-HY-170405-10MG,MCE-HY-170405-25MG,MCE-HY-170405-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

YB-3-17 is a bifunctional molecule, that inhibits mTOR (IC50=0.22 nM) or degrades G1 to S phase transition 1 gene (GSPT1, DC50=5 nM) in a PROTAC mechanism. YB-3-17 exhibits antiproliferative activity in multi glioblastoma cell lines with IC50 of nanomolare levels. YB-3-17 exhibits antitumor efficacy in mouse models[1]. (Pink: ligand for target protein (HY-170407), Black: linker (HY-A0102), Blue: ligand for E3 ligase Cereblon (HY-14658))

Produkteigenschaften

• Molekulargewicht: 745.79
• CAS Nummer: [2940242-88-4]
• Formel: C38H39N11O6
• Target-Kategorie: mTOR,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound