CD73-IN-19 (Compound 4ab) is a CD73 inhibitor (with a 44% inhibition rate of CD73 enzymatic activity at 100 µM). CD73-IN-19 (at 10 µM and 100 µM) can completely antagonize the blockade of T cell proliferation induced by TCR (T cell receptor) triggering (which is induced by CD73 activity), and it can also inhibit the hA2A receptor activity in HEK-293 cells (Ki is 3.31 µM). CD73-IN-19 holds promise for research in the field of immune diseases[1].
Molekulargewicht:
355.41
CAS Nummer:
[333329-22-9]
Formel:
C18H17N3O3S
Target-Kategorie:
CD73
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
