CD73-IN-19 (Compound 4ab) is a CD73 inhibitor (with a 44% inhibition rate of CD73 enzymatic activity at 100 µM). CD73-IN-19 (at 10 µM and 100 µM) can completely antagonize the blockade of T cell proliferation induced by TCR (T cell receptor) triggering (which is induced by CD73 activity), and it can also inhibit the hA2A receptor activity in HEK-293 cells (Ki is 3.31 µM). CD73-IN-19 holds promise for research in the field of immune diseases[1].
Molecular Weight:
355.41
CAS Number:
[333329-22-9]
Formula:
C18H17N3O3S
Target:
CD73
Application Notes:
MCE Product type: Reference compound
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