Dual Cathepsin L/JAK-IN-1, CAS [[2450279-41-9]] Preis auf Anfrage

Artikelnummer: MCE-HY-170772
Artikelname: Dual Cathepsin L/JAK-IN-1, CAS [[2450279-41-9]] Preis auf Anfrage
Artikelnummer: MCE-HY-170772
Hersteller Artikelnummer: HY-170772
Alternativnummer: MCE-HY-170772-5MG,MCE-HY-170772-25MG,MCE-HY-170772-10MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Dual Cathepsin L/JAK-IN-1 (Compound A8) is a dual inhibitor of Cathepsin L (CTSL) and JAK, with IC50 values of 0.68 µM, 337.1 nM, 5.251 nM, 27.29 nM, and 172.6 nM for CTSL, JAK1/2/3, and TYK2, respectively. Dual Cathepsin L/JAK-IN-1 effectively blocks the activation of the MAPK, NF-kappaB, and JAK/STAT signaling pathways, leading to significant anti-inflammatory therapeutic effects. Dual Cathepsin L/JAK-IN-1 can be used in research on acute lung injury (ALI)[1].
Molekulargewicht: 351.83
Reinheit: 98.47
CAS Nummer: [2450279-41-9]
Formel: C19H18ClN5
Target-Kategorie: Cathepsin,Interleukin Related,JAK,p38 MAPK,STAT
Anwendungsbeschreibung: MCE Product type: Reference compound