P162-0948, CAS [[1358201-44-1]] Preis auf Anfrage

Artikelnummer: MCE-HY-170813
Artikelname: P162-0948, CAS [[1358201-44-1]] Preis auf Anfrage
Artikelnummer: MCE-HY-170813
Hersteller Artikelnummer: HY-170813
Alternativnummer: MCE-HY-170813-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
P162-0948 is a selective CDK8 inhibitor with an IC50 value of 50.4 nM. P162-0948 reduces cell migration and protein expression of EMT-related proteins in A549 human alveolar epithelial cell lines. P162-0948 reduces phosphorylation of Smad, which suggests disruption of the TGF-beta/Smad signaling pathway. P162-0948 is promising for research of pulmonary fibrosis[1].
Molekulargewicht: 362.36
CAS Nummer: [1358201-44-1]
Formel: C20H15FN4O2
Target-Kategorie: CDK,TGF-beta/Smad
Anwendungsbeschreibung: MCE Product type: Reference compound