TFGF-18, CAS [[2222662-20-4]] Preis auf Anfrage

Artikelnummer: MCE-HY-171031
Artikelname: TFGF-18, CAS [[2222662-20-4]] Preis auf Anfrage
Artikelnummer: MCE-HY-171031
Hersteller Artikelnummer: HY-171031
Alternativnummer: MCE-HY-171031-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
TFGF-18 is a GSK-3beta inhibitor (IC50: 0.59 µM). TFGF-18 inhibits LPS-induced microglia activation and proinflammatory mediators release via inhibiting GSK-3beta and downstream p65/NF-kappaB signaling. TFGF-18 inhibits neuronal apoptosis and oxidative stress, inhibits expressions of Bax, caspase3 and cleaved-caspase3 and increases the expression of Bcl-2. TFGF-18 has neuroprotection effect, inhibit neuroinflammation and attenuates cognitive impairment[1][2].
Molekulargewicht: 613.53
CAS Nummer: [2222662-20-4]
Formel: C28H30F3NO11
Target-Kategorie: Apoptosis,Bcl-2 Family,Caspase,GSK-3,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung: MCE Product type: Reference compound