SK2188, CAS [[3038446-94-2]]

Produktübersicht

• Artikelname: SK2188, CAS [[3038446-94-2]]
• Artikelnummer: MCE-HY-171767
• Hersteller Artikelnummer: HY-171767
• Alternativnummer: MCE-HY-171767-50MG,MCE-HY-171767-5MG,MCE-HY-171767-25MG,MCE-HY-171767-1MG,MCE-HY-171767-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: JB325

Produktbeschreibung

SK2188 is a highly efficient and selective PROTAC degrader targeting AURKA (DC50 = 3.9 nM). SK2188 induces DNA damage and cell apoptosis. SK2188 indirectly degrades MYCN, inhibits tumor cell proliferation, and provides insights into the study of MYCN-amplified neuroblastoma (Pink: AURKA ligand: MK-5108 (HY-13252), Blue: Thalidomide (HY-14658), Black: Linker: Amino-PEG4-alcohol (HY-W008005))[1].

Produkteigenschaften

• Molekulargewicht: 893.38
• Reinheit: 99.87
• CAS Nummer: [3038446-94-2]
• Formel: C43H46ClFN6O10S
• Target-Kategorie: Apoptosis,Aurora Kinase,Caspase,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound