FC-14369, CAS [[3066894-28-5]]

Produktübersicht

• Artikelname: FC-14369, CAS [[3066894-28-5]]
• Artikelnummer: MCE-HY-171860
• Hersteller Artikelnummer: HY-171860
• Alternativnummer: MCE-HY-171860-10MG,MCE-HY-171860-5MG,MCE-HY-171860-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

FC-14369 is a PROTAC degrader targeting HIV-1 Nef protein with a DC50 value of 160 nM. FC-14369 binds to both Nef and Cereblon E3 ubiquitin ligase via its bifunctional structure, inducing Nef ubiquitination and proteasomal degradation to restore cell-surface CD4 and MHC-I expression and inhibit HIV-1 replication. FC-14369 can be used in research on HIV infection and AIDS[1]. (Pink: Nef ligand-2 (HY-171862), Black: Ethylenediamine (HY-Y0275), Blue: Thalidomide (HY-14658))

Produkteigenschaften

• Molekulargewicht: 855.22
• Reinheit: 97.85
• CAS Nummer: [3066894-28-5]
• Formel: C42H34ClF3N8O7
• Target-Kategorie: HIV,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound