FC-14369, CAS [[3066894-28-5]]

Product Overview

• Article Name: FC-14369, CAS [[3066894-28-5]]
• Biozol Catalog Number: MCE-HY-171860
• Supplier Catalog Number: HY-171860
• Alternative Catalog Number: MCE-HY-171860-1MG,MCE-HY-171860-10MG,MCE-HY-171860-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

FC-14369 is a PROTAC degrader targeting the HIV-1 Nef protein, with a DC50 value of 160 nM. Through its bifunctional structure, FC-14369 binds to Nef and the Cereblon E3 ubiquitin ligase, induces Nef ubiquitination and proteasomal degradation, restores the expression of cell-surface CD4 and MHC-I, and inhibits HIV-1 replication. FC-14369 can be used in research on HIV infection and AIDS. FC-14369 is applicable to studies related to HIV-1 infection[1].

Product Properties

• Molecular Weight: 855.22
• Purity: 97.85
• CAS Number: [3066894-28-5]
• Formula: C42H34ClF3N8O7
• Target: HIV,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound