BI-4659, CAS [[894784-05-5]]

Produktübersicht

• Artikelname: BI-4659, CAS [[894784-05-5]]
• Artikelnummer: MCE-HY-171878
• Hersteller Artikelnummer: HY-171878
• Alternativnummer: MCE-HY-171878-5MG,MCE-HY-171878-25MG,MCE-HY-171878-50MG,MCE-HY-171878-100MG,MCE-HY-171878-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

BI-4659 is a TGFbetaRI and PDGFRalpha inhibitor with IC50 values of 19 nM and 99 nM, respectively. BI-4659 inhibits the kinase activities of TGFbetaRI and PDGFRalpha, blocks the downstream TGFbetaRI signaling pathway, and reduces the phosphorylation level of Smad2/3 without altering the expression of TGF-beta1. BI-4659 is applicable to research related to pulmonary fibrosis, cancer, and renal ischemia-reperfusion injury[1][2].

Produkteigenschaften

• Molekulargewicht: 440.54
• Reinheit: 99.78
• CAS Nummer: [894784-05-5]
• Formel: C27H28N4O2
• Target-Kategorie: PDGFR,TGF-beta/Smad,TGF-beta Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound