PD-L1/HDAC6-IN-1, CAS [[2834094-36-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: PD-L1/HDAC6-IN-1, CAS [[2834094-36-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-172200
• Hersteller Artikelnummer: HY-172200
• Alternativnummer: MCE-HY-172200-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PD-L1/HDAC6-IN-1 (Compound HP29) is the inhibitor for PD-L1 and HDAC6 that inhibits the PD-L1/PD-1 interaction and HDAC6 with an IC50 of 26.8 nM and 69 nM. PD-L1/HDAC6-IN-1 enhances the killing ability of Jurkat T cells against HepG2 cells with an IC50 of 3.4 µM. PD-L1/HDAC6-IN-1 exhibits good pharmacokinetics characteristics in rats with a drug exposure of 871.62 ngh/mL, and exhibits antitumor activity in mouse B16-F10 xenograft models[1].

Produkteigenschaften

• Molekulargewicht: 447.57
• CAS Nummer: [2834094-36-7]
• Formel: C27H33N3O3
• Target-Kategorie: HDAC,PD-1/PD-L1

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound