PD-L1/HDAC6-IN-1, CAS [[2834094-36-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-172200
Supplier Catalog Number:
HY-172200
Alternative Catalog Number:
MCE-HY-172200-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PD-L1/HDAC6-IN-1 (Compound HP29) is the inhibitor for PD-L1 and HDAC6 that inhibits the PD-L1/PD-1 interaction and HDAC6 with an IC50 of 26.8 nM and 69 nM. PD-L1/HDAC6-IN-1 enhances the killing ability of Jurkat T cells against HepG2 cells with an IC50 of 3.4 µM. PD-L1/HDAC6-IN-1 exhibits good pharmacokinetics characteristics in rats with a drug exposure of 871.62 ngh/mL, and exhibits antitumor activity in mouse B16-F10 xenograft models[1].
Molecular Weight:
447.57
CAS Number:
[2834094-36-7]
Formula:
C27H33N3O3
Target:
HDAC,PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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