PROTAC cGAS degrader-1, CAS [[3118499-89-8]]

Produktübersicht

• Artikelname: PROTAC cGAS degrader-1, CAS [[3118499-89-8]]
• Artikelnummer: MCE-HY-172208
• Hersteller Artikelnummer: HY-172208
• Alternativnummer: MCE-HY-172208-5MG,MCE-HY-172208-1MG,MCE-HY-172208-25MG,MCE-HY-172208-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC cGAS degrader-1 is a potent and selective cGAS PROTAC degrader, with DC50 values of 0.9 µM and 4.6 µM in THP-1 and RAW 264.7 cells, respectively. PROTAC cGAS degrader-1 induces proteasome-mediated degradation of cGAS, inhibits the cGAS signaling pathway, and attenuates double-stranded DNA-induced activation of cGAS in human and mouse cells. PROTAC cGAS degrader-1 is applicable to research related to ulcerative colitis[1].

Produkteigenschaften

• Molekulargewicht: 714.60
• Reinheit: 99.07
• CAS Nummer: [3118499-89-8]
• Formel: C36H33Cl2N7O5
• Target-Kategorie: Cyclic GMP-AMP Synthase,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound