DNMT1-IN-5, CAS [[2982511-19-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: DNMT1-IN-5, CAS [[2982511-19-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-172217
• Hersteller Artikelnummer: HY-172217
• Alternativnummer: MCE-HY-172217-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

DNMT1-IN-5 (Compound 55) is the inhibitor for DNMT that inhibits DNMT1 and DNMT3A with IC50 of 2.42 µM and 14.4 µM. DNMT1-IN-5 exhibits antiproliferative activity in a variety of cancer cell lines (IC50s for TMD-8, DOHH2, MOLM-13, THP-1, RPIM-8226 and HCT116 are 0.19-2.37 µM), arrests the cell cycle at G2/M phase, and induces apoptosis in TMD-8 and DOHH2 cells. DNMT1-IN-5 exhibits antitumor efficacy in TMD-8 xenograft mouse models[1].

Produkteigenschaften

• Molekulargewicht: 437.56
• CAS Nummer: [2982511-19-1]
• Formel: C24H32FN7
• Target-Kategorie: Apoptosis,DNA Methyltransferase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound