DNMT1-IN-5, CAS [[2982511-19-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-172217
Supplier Catalog Number:
HY-172217
Alternative Catalog Number:
MCE-HY-172217-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
DNMT1-IN-5 (Compound 55) is the inhibitor for DNMT that inhibits DNMT1 and DNMT3A with IC50 of 2.42 µM and 14.4 µM. DNMT1-IN-5 exhibits antiproliferative activity in a variety of cancer cell lines (IC50s for TMD-8, DOHH2, MOLM-13, THP-1, RPIM-8226 and HCT116 are 0.19-2.37 µM), arrests the cell cycle at G2/M phase, and induces apoptosis in TMD-8 and DOHH2 cells. DNMT1-IN-5 exhibits antitumor efficacy in TMD-8 xenograft mouse models[1].
Molecular Weight:
437.56
CAS Number:
[2982511-19-1]
Formula:
C24H32FN7
Target:
Apoptosis,DNA Methyltransferase
Application Notes:
MCE Product type: Reference compound
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