GSK-3alpha/beta-IN-1, CAS [[1574354-24-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: GSK-3alpha/beta-IN-1, CAS [[1574354-24-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-172586
• Hersteller Artikelnummer: HY-172586
• Alternativnummer: MCE-HY-172586-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GSK-3alpha/beta-IN-1 is GSK-3alpha/beta inhibitor with IC50 s of 0.265 µM and 0.255 µM for GSK-3alpha and GSK-3beta, respectively. GSK-3alpha/beta-IN-1 also inhibits PKA with an IC50 of 0.188 µM. GSK-3alpha/beta-IN-1 potently inhibits cell viability of three Glioblastoma (GBM) cell lines (IC50 : 3-6 µM, 72 h) with no toxicity to human astrocytes and good metabolic stability. GSK-3alpha/beta-IN-1 has potential CNS activity in all-human blood-brain barrier (BBB) model of GBM[1].

Produkteigenschaften

• Molekulargewicht: 343.38
• CAS Nummer: [1574354-24-7]
• Formel: C21H17N3O2
• Target-Kategorie: GSK-3,PKA

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound