GSK-3alpha/beta-IN-1, CAS [[1574354-24-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-172586
Supplier Catalog Number:
HY-172586
Alternative Catalog Number:
MCE-HY-172586-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
GSK-3alpha/beta-IN-1 is GSK-3alpha/beta inhibitor with IC50 s of 0.265 µM and 0.255 µM for GSK-3alpha and GSK-3beta, respectively. GSK-3alpha/beta-IN-1 also inhibits PKA with an IC50 of 0.188 µM. GSK-3alpha/beta-IN-1 potently inhibits cell viability of three Glioblastoma (GBM) cell lines (IC50 : 3-6 µM, 72 h) with no toxicity to human astrocytes and good metabolic stability. GSK-3alpha/beta-IN-1 has potential CNS activity in all-human blood-brain barrier (BBB) model of GBM[1].
Molecular Weight:
343.38
CAS Number:
[1574354-24-7]
Formula:
C21H17N3O2
Target:
GSK-3,PKA
Application Notes:
MCE Product type: Reference compound
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