HDAC/PSMD14-IN-1, CAS [[3062141-62-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-172878
Hersteller Artikelnummer:
HY-172878
Alternativnummer:
MCE-HY-172878-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
HDAC/PSMD14-IN-1 (Compound 8B) is a thiolutin derivative. HDAC/PSMD14-IN-1 is a orally active dual-target inhibitor of PSMD14/HDAC1 (IC50 238.7 nM/141.2 nM, respectively). HDAC/PSMD14-IN-1 has good cytotoxicity against ESCC cell lines (IC50: 30-250 nM) and effectively reverses epithelial-mesenchymal transition (EMT). HDAC/PSMD14-IN-1 can induce apoptosis. HDAC/PSMD14-IN-1 has anti-tumor activity in a KYSE30 cell mouse xenograft model. HDAC/PSMD14-IN-1 can be used in anti-esophageal cancer research[1].
Molekulargewicht:
432.56
CAS Nummer:
[3062141-62-9]
Formel:
C20H24N4O3S2
Target-Kategorie:
Apoptosis,HDAC,Small Interfering RNA (siRNA)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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