HDAC/PSMD14-IN-1, CAS [[3062141-62-9]] Preis auf Anfrage

Artikelnummer: MCE-HY-172878
Artikelname: HDAC/PSMD14-IN-1, CAS [[3062141-62-9]] Preis auf Anfrage
Artikelnummer: MCE-HY-172878
Hersteller Artikelnummer: HY-172878
Alternativnummer: MCE-HY-172878-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
HDAC/PSMD14-IN-1 (Compound 8B) is a thiolutin derivative. HDAC/PSMD14-IN-1 is a orally active dual-target inhibitor of PSMD14/HDAC1 (IC50 238.7 nM/141.2 nM, respectively). HDAC/PSMD14-IN-1 has good cytotoxicity against ESCC cell lines (IC50: 30-250 nM) and effectively reverses epithelial-mesenchymal transition (EMT). HDAC/PSMD14-IN-1 can induce apoptosis. HDAC/PSMD14-IN-1 has anti-tumor activity in a KYSE30 cell mouse xenograft model. HDAC/PSMD14-IN-1 can be used in anti-esophageal cancer research[1].
Molekulargewicht: 432.56
CAS Nummer: [3062141-62-9]
Formel: C20H24N4O3S2
Target-Kategorie: Apoptosis,HDAC,Small Interfering RNA (siRNA)
Anwendungsbeschreibung: MCE Product type: Reference compound