HDAC/PSMD14-IN-1, CAS [[3062141-62-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-172878
Supplier Catalog Number:
HY-172878
Alternative Catalog Number:
MCE-HY-172878-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
HDAC/PSMD14-IN-1 (Compound 8B) is a thiolutin derivative. HDAC/PSMD14-IN-1 is a orally active dual-target inhibitor of PSMD14/HDAC1 (IC50 238.7 nM/141.2 nM, respectively). HDAC/PSMD14-IN-1 has good cytotoxicity against ESCC cell lines (IC50: 30-250 nM) and effectively reverses epithelial-mesenchymal transition (EMT). HDAC/PSMD14-IN-1 can induce apoptosis. HDAC/PSMD14-IN-1 has anti-tumor activity in a KYSE30 cell mouse xenograft model. HDAC/PSMD14-IN-1 can be used in anti-esophageal cancer research[1].
Molecular Weight:
432.56
CAS Number:
[3062141-62-9]
Formula:
C20H24N4O3S2
Target:
Apoptosis,HDAC,Small Interfering RNA (siRNA)
Application Notes:
MCE Product type: Reference compound
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