PI3K-IN-58, CAS [[3067572-78-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: PI3K-IN-58, CAS [[3067572-78-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-172886
• Hersteller Artikelnummer: HY-172886
• Alternativnummer: MCE-HY-172886-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PI3K-IN-58 (Compound 17f) is a PI3Kalpha inhibitor (IC50: 0.039 µM). PI3K-IN-58 exhibits significant antiproliferative effects on PC-3, 22RV1, MDA-MB-231 and MDA-MB-453 cell lines with IC50s of 3.48 µM, 1.06 µM, 2.21 µM and 0.93 µM, respectively. PI3K-IN-58 induces apoptosis by downregulating the expression levels of anti-apoptotic proteins Bcl-XL and Bcl-2 and upregulating the expression of anti-apoptosis protein BAX. PI3K-IN-58 can be used in PI3K-targeted cancer research[1].

Produkteigenschaften

• Molekulargewicht: 450.51
• CAS Nummer: [3067572-78-2]
• Formel: C22H22N6O3S
• Target-Kategorie: Apoptosis,Bcl-2 Family,PI3K

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound