W23-1006 is a selective and covalent ALKBH5 inhibitor. W23-1006 binds to the ALKBH5 C200 residue with an IC50 value of 3.848 µM. W23-1006 shows ~30- and 8-fold stronger inhibitory activity than that against FTO and ALKBH3, respectively. W23-1006 can be used for the study of triple-negative breast cancer (TNBC)[1].
Molekulargewicht:
418.20
Reinheit:
97.15
CAS Nummer:
[3035498-92-8]
Formel:
C17H12BrN3O5
Target-Kategorie:
Anaplastic lymphoma kinase (ALK),Apoptosis
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten