W23-1006 is a selective and covalent ALKBH5 inhibitor. W23-1006 binds to the ALKBH5 C200 residue with an IC50 value of 3.848 µM. W23-1006 shows ~30- and 8-fold stronger inhibitory activity than that against FTO and ALKBH3, respectively. W23-1006 can be used for the study of triple-negative breast cancer (TNBC)[1].
Molecular Weight:
418.20
Purity:
97.15
CAS Number:
[3035498-92-8]
Formula:
C17H12BrN3O5
Target:
Anaplastic lymphoma kinase (ALK),Apoptosis
Application Notes:
MCE Product type: Reference compound
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