TRPC4/5-IN-3, CAS [[3053390-98-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: TRPC4/5-IN-3, CAS [[3053390-98-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-173024
• Hersteller Artikelnummer: HY-173024
• Alternativnummer: MCE-HY-173024-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

TRPC4/5-IN-3 (Compound 32) is the orally active inhibitor for transient receptor potential canonical channel 4/5 (TRPC4/5) with IC50 of 3.6 nM and 5.5 nM. TRPC4/5-IN-3 inhibits hERG channel with IC50 of 6.5 µM. TRPC4/5-IN-3 exhibits good metabolic stability in human/rat/mouse liver microsomes. TRPC4/5-IN-3 exhibits antidepressant and anxiolytic activity in mouse models, exhibits good pharmacokinetic characteristics in mouse with an oral bioavailability of 87%[1].

Produkteigenschaften

• Molekulargewicht: 486.44
• CAS Nummer: [3053390-98-7]
• Formel: C22H23F5N4O3
• Target-Kategorie: TRP Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound