TRPC4/5-IN-3, CAS [[3053390-98-7]] Preis auf Anfrage

Product Overview

• Article Name: TRPC4/5-IN-3, CAS [[3053390-98-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-173024
• Supplier Catalog Number: HY-173024
• Alternative Catalog Number: MCE-HY-173024-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

TRPC4/5-IN-3 (Compound 32) is the orally active inhibitor for transient receptor potential canonical channel 4/5 (TRPC4/5) with IC50 of 3.6 nM and 5.5 nM. TRPC4/5-IN-3 inhibits hERG channel with IC50 of 6.5 µM. TRPC4/5-IN-3 exhibits good metabolic stability in human/rat/mouse liver microsomes. TRPC4/5-IN-3 exhibits antidepressant and anxiolytic activity in mouse models, exhibits good pharmacokinetic characteristics in mouse with an oral bioavailability of 87%[1].

Product Properties

• Molecular Weight: 486.44
• CAS Number: [3053390-98-7]
• Formula: C22H23F5N4O3
• Target: TRP Channel

Application Notes

• Application Notes: MCE Product type: Reference compound