CLPP-2068, CAS [[3104462-62-3]]

Artikelnummer: MCE-HY-173048
Artikelname: CLPP-2068, CAS [[3104462-62-3]]
Artikelnummer: MCE-HY-173048
Hersteller Artikelnummer: HY-173048
Alternativnummer: MCE-HY-173048-10MMX1ML,MCE-HY-173048-5MG,MCE-HY-173048-10MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
CLPP-2068 is the orally active activator for human caseinolytic protease P (HsClpP) with an EC50 of 50.4 nM. CLPP-2068 exhibits anti-proliferative efficacy in OCI-LY10 cancer cell with an IC50 of 5.2 nM. CLPP-2068 decreases mitochondrial membrane potential, increases mitochondrial ROS levels, and induces mitochondrial dysfunction. CLPP-2068 arrests the cell cycle at G1 phase, and induces apoptosis in cell OCI-LY10. CLPP-2068 exhibits antitumor activity in mouse xenograft models[1].
Molekulargewicht: 464.36
Reinheit: 97.41
CAS Nummer: [3104462-62-3]
Formel: C23H22BrN5O
Target-Kategorie: Apoptosis,ClpP,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung: MCE Product type: Reference compound