(S,R,S)-AHPC-Boc derivative 1, CAS [[2086298-33-9]]

Produktübersicht

• Artikelname: (S,R,S)-AHPC-Boc derivative 1, CAS [[2086298-33-9]]
• Artikelnummer: MCE-HY-173097
• Hersteller Artikelnummer: HY-173097
• Alternativnummer: MCE-HY-173097-100MG,MCE-HY-173097-50MG,MCE-HY-173097-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: VH032-Boc derivative 1

Produktbeschreibung

(S,R,S)-AHPC-Boc derivative 1 (Compound 80-9, VH032-Boc derivative 1) is a selective proteasomal degrader targeting MALT1, which recruits the E3 ubiquitin ligase CRBN to form a ternary complex with MALT1, leading to ubiquitination and subsequent proteasomal degradation of MALT1. (S,R,S)-AHPC-Boc derivative 1 inhibits the NF-kappaB signaling pathway by disrupting the CBM complex, demonstrating potential for inducing apoptosis in ABC-DLBCL cells. (S,R,S)-AHPC-Boc derivative 1 is promising for research of MALT1-dependent cancers, such as diffuse large B-cell lymphoma (DLBCL)[1].

Produkteigenschaften

• Molekulargewicht: 560.71
• Reinheit: 98.56
• CAS Nummer: [2086298-33-9]
• Formel: C28H40N4O6S
• Target-Kategorie: MALT1

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound