15-LOX-IN-2 (Compound 2a) is an orally active COX-2/15-LOX inhibitor and a partial agonist of PPARgamma. 15-LOX-IN-2 has anti-inflammatory activity and inhibits the levels of 20-HETE, IL-1beta and TNF-alpha in RAW 264.7 cells treated with LPS (HY-D1056). In addition, 15-LOX-IN-2 has significant glucose uptake capacity in the absence of insulin. 15-LOX-IN-2 can be used for the research of metabolic diseases[1].
Molekulargewicht:
312.39
Formel:
C17H16N2O2S
Target-Kategorie:
COX,Interleukin Related,Lipoxygenase,PPAR
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
