Hapalindole Q, CAS [[106928-29-4]] Preis auf Anfrage

Artikelnummer: MCE-HY-173150
Artikelname: Hapalindole Q, CAS [[106928-29-4]] Preis auf Anfrage
Artikelnummer: MCE-HY-173150
Hersteller Artikelnummer: HY-173150
Alternativnummer: MCE-HY-173150-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Hapalindole Q (Compound (+)-1) is an autophagy (Autophagy) inhibitor targeting YAP1. Hapalindole Q binds to the Hippo pathway transcription factor YAP1 with a Kd of 9.13 µM and induces its degradation via the chaperone-mediated autophagy (CMA) pathway. This process inhibits Rab7-mediated fusion of autophagosomes and lysosomes, thereby reducing overall autophagy levels without affecting lysosomal function. Hapalindole Q holds promise for research in cancer (e.g., liver cancer, breast cancer, etc.)[1].
Molekulargewicht: 336.49
CAS Nummer: [106928-29-4]
Formel: C21H24N2S
Target-Kategorie: YAP
Anwendungsbeschreibung: MCE Product type: Reference compound