Hapalindole Q, CAS [[106928-29-4]] Preis auf Anfrage

Catalog Number: MCE-HY-173150
Article Name: Hapalindole Q, CAS [[106928-29-4]] Preis auf Anfrage
Biozol Catalog Number: MCE-HY-173150
Supplier Catalog Number: HY-173150
Alternative Catalog Number: MCE-HY-173150-1UNIT
Manufacturer: MedchemExpress
Category: Biochemikalien
Hapalindole Q (Compound (+)-1) is an autophagy (Autophagy) inhibitor targeting YAP1. Hapalindole Q binds to the Hippo pathway transcription factor YAP1 with a Kd of 9.13 µM and induces its degradation via the chaperone-mediated autophagy (CMA) pathway. This process inhibits Rab7-mediated fusion of autophagosomes and lysosomes, thereby reducing overall autophagy levels without affecting lysosomal function. Hapalindole Q holds promise for research in cancer (e.g., liver cancer, breast cancer, etc.)[1].
Molecular Weight: 336.49
CAS Number: [106928-29-4]
Formula: C21H24N2S
Target: YAP
Application Notes: MCE Product type: Reference compound