Hapalindole Q, CAS [[106928-29-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-173150
Supplier Catalog Number:
HY-173150
Alternative Catalog Number:
MCE-HY-173150-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Hapalindole Q (Compound (+)-1) is an autophagy (Autophagy) inhibitor targeting YAP1. Hapalindole Q binds to the Hippo pathway transcription factor YAP1 with a Kd of 9.13 µM and induces its degradation via the chaperone-mediated autophagy (CMA) pathway. This process inhibits Rab7-mediated fusion of autophagosomes and lysosomes, thereby reducing overall autophagy levels without affecting lysosomal function. Hapalindole Q holds promise for research in cancer (e.g., liver cancer, breast cancer, etc.)[1].
Molecular Weight:
336.49
CAS Number:
[106928-29-4]
Formula:
C21H24N2S
Target:
YAP
Application Notes:
MCE Product type: Reference compound
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