SARM1-IN-4, CAS [[3069378-18-0]]

Artikelnummer: MCE-HY-173276
Artikelname: SARM1-IN-4, CAS [[3069378-18-0]]
Artikelnummer: MCE-HY-173276
Hersteller Artikelnummer: HY-173276
Alternativnummer: MCE-HY-173276-5MG,MCE-HY-173276-10MG,MCE-HY-173276-25MG,MCE-HY-173276-50MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
SARM1-IN-4 is an orally active SARM1 inhibitor, with IC50 values of 0.31 µM, 0.318 µM, and 0.253 µM against human, mouse, and rat SARM1, respectively. SARM1-IN-4 reduces plasma neurofilament light chain levels and blocks warfarin-induced axonal degeneration. SARM1-IN-4 exhibits neuroprotective activity in mouse models, but paradoxical SARM1 activation occurs at low oral doses. SARM1-IN-4 can be used in studies of peripheral nerve injury[1].
Molekulargewicht: 285.29
CAS Nummer: [3069378-18-0]
Formel: C13H17F2N3O2
Target-Kategorie: Toll-like Receptor (TLR)
Anwendungsbeschreibung: MCE Product type: Reference compound