Brefeldin A 4-O-nicotinate, CAS [[3035018-34-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: Brefeldin A 4-O-nicotinate, CAS [[3035018-34-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-173280
• Hersteller Artikelnummer: HY-173280
• Alternativnummer: MCE-HY-173280-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CHNQD-01228

Produktbeschreibung

Brefeldin A 4-O-nicotinate (CHNQD-01228) is a dual inhibitor of Arf1 and BMX proteins. The IC50 value for the proliferation of T24 cells is 0.22 µM. It can also dose-dependently inhibit the migration and colony formation of T24 cells, induce G1 phase arrest and trigger Apoptosis. Brefeldin A 4-O-nicotinate exerts its anti-cancer activity by targeting the BMX protein to inhibit the AKT/p-AKT and STAT3/p-STAT3 signaling pathways, as well as by inhibiting the Arf1 protein to eliminate bladder cancer stem cells and activate anti-tumor immunity. Brefeldin A 4-O-nicotinate can be used in the research related to bladder cancer[1].

Produkteigenschaften

• Molekulargewicht: 385.45
• CAS Nummer: [3035018-34-6]
• Formel: C22H27NO5
• Target-Kategorie: Arf Family GTPase,BMX Kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound